Meningioma 1 antibody

Catalog No. ABIN7116478

This Rabbit Polyclonal antibody specifically detects Meningioma 1 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for Meningioma 1 antibody (ABIN7116478)

Target: Meningioma 1 (MN1) (MN1 proto-oncogene (MN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Meningioma 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-Meningioma 1 Antibody

Purpose: MN1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: meningioma(disrupted in balanced translocation) 1

Isotype: IgG

Application Details

Application Notes: IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Meningioma 1

Target: Meningioma 1 (MN1) (MN1 proto-oncogene (MN1))

Alternative Name: MN1

Background:

Synonyms: Transcriptional activator MN1|Probable tumor suppressor protein MN1|MN1

Background: Transcriptional activator which specifically regulates expression of TBX22 in the posterior region of the developing palate. Required during later stages of palate development for growth and medial fusion of the palatal shelves. Promotes maturation and normal function of calvarial osteoblasts, including expression of the osteoclastogenic cytokine TNFSF11/RANKL. Necessary for normal development of the membranous bones of the skull(By similarity). May play a role in tumor suppression(Probable).

Gene ID: 4330

UniProt: Q10571